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Reflux esophagitis with metaplastic epithelium in cats
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Reflux esophagitis is commonly seen in men and also in dogs, sometimes in cats. Often the problem is associated with a chronic or chronic-relapsing gastritis. In this very interesting case report, the three affected cats had changes of the epithelium of the distal esophagus resembling the Barrett´s esophagus in humans.
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Gastroesophageal reflux is a relatively common condition in dogs and cats and may lead to secondary reflux esophagitis.
A consequence of chronic gastroesophageal reflux that is well described in humans is BarrettÂ’s esophagus, which is the replacement of the normal squamous epithelium of the distal esophagus with metaplastic columnar epithelium.
Three cats with clinical and endoscopic signs of chronic esophagitis had metaplastic columnar epithelium on biopsy of the distal esophageal mucosa.
Suspected underlying causes were cardial incompetence and sliding hiatal hernia.
Two cats had complete resolution of the clinical signs after treatment. One cat was euthanized.
Source: Massimo Gualtieri, DVM, PhD and Daniela Olivero (2006): Reflux Esophagitis in Three Cats Associated With Metaplastic Columnar Esophageal Epithelium. In: Journal of the American Animal Hospital Association 42:65-70 (2006)
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