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Effect of breed on anatomy of portosystemic shunts
A very interesting question and a very interesting study on nearly 250 animals: Do species and breed have an effect on the anatomy of portosystemic vascular anomalies in dogs and cats? A large retrospective study from Australia.

233 dogs and nine cats presenting to the University Veterinary Centre, Sydney, were included in this study.
Case records were evaluated for breed, sex, age, anatomical and histological diagnosis.
Cases were included when a portosystemic vascular anomaly resulted from a congenital or developmental abnormality of the liver or portal venous system.

RESULTS: Disease conditions included single congenital portosystemic shunt with patent portal vasculature (214 dogs, nine cats), portal vein aplasia (nine dogs), multiple acquired shunts resulting from portal vein hypoplasia (seven dogs), biliary atresia (one dog) and microvascular dysplasia (one dog).

One Maltese had a single, congenital shunt and multiple acquired shunts resulting from hepatic cirrhosis.

Breeds that were significantly over-represented included the Maltese, Silky Terrier, Australian Cattle Dog, Bichon Frise, Shih Tzu, Miniature Schnauzer, Border Collie, Jack Russell Terrier, Irish Wolfhound and Himalayan cat.

Bichon Frise with shunts were significantly more likely to be female than male (12:2, P < 0.001).

Two hundred and fourteen dogs (91.4%), and all cats, had shunts that were amenable to attenuation.

Inoperable shunts occurred in 19 dogs (8.2%). Fifty six of 61 (92%) operable shunts in large breed dogs were intrahepatic, versus 10/153 (7%) in small breeds (P < 0.0001).

Breeds that were not predisposed to portosystemic shunts were significantly more likely to have unusual or inoperable shunts than dogs from predisposed breeds (29% versus 7.6%, P < 0.0001).

No significant relationship between breed and shunt type could be determined in cats.

CONCLUSION: Breed has a significant influence on shunt anatomy in dogs.
Animals presenting with signs of portosystemic shunting may suffer from a wide range of operable or inoperable conditions.
Veterinarians should be aware that unusual or inoperable shunts are much more likely to occur in breeds that are not predisposed to congenital portosystemic shunts.



Source: Hunt GB. (2004): Effect of breed on anatomy of portosystemic shunts resulting from congenital diseases in dogs and cats: a review of 242 cases. In: Aust Vet J. 2004 Dec;82(12):746-9.



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SMALL ANIMAL PRACTICE

Reference intervals for blood parameters in Shetland Sheepdogsmembers
Several breeds have physiological peculiarities that induce variations in reference intervals (RIs) compared with the general canine population. Shetland sheepdogs (SSs) are reported to be more predisposed to different diseases (eg, hyperlipidemia, gallbladder mucocele, and hypothyroidism). Consequently, a breedâ€specific approach is more often required. Thus, the aim of this study was to determine whether the RIs of the general canine population could be applied to that of SSs, and to generate breedâ€specific RIs, where appropriate.

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