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Novel manifestation of masticatory muscle myositis
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The immune-mediated disease masticatory muscle myositis is well-known in Cavalier King Charles spaniels and has a hereditary component. This very informative case report from the UK describes the same problem, a novel manifestation of this disease, in three littermates.
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Clinical signs, including difficulty in opening the mouth (trismus), were seen in three of four 12-week-old cavalier King Charles spaniel littermates.
Diagnosis was established by 2M immunohistochemistry, supported by characteristic histopathological changes in affected temporal muscle.
Treatment using corticosteroids at immune-modifying doses resulted in resolution of clinical signs in all the affected animals.
Masticatory muscle myositis should be considered as a differential diagnosis in groups of young dogs with clinical signs of myositis localised to the head.
Source: Pitcher GD, Hahn CN. (2007): Atypical masticatory muscle myositis in three cavalier King Charles spaniel littermates. In: J Small Anim Pract. 2007 Apr;48(4):226-8.
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