Clinical signs were characterised by dehydration and various neurological deficits including seizures. Most striking laboratory abnormalities were hypernatremia, hypocalcemia, hyperphosphatemia, and polycythemia.
Despite intensive treatment the dog died, whereas the cats recovered completely.
In face of possible severe and potentially fatal metabolic abnormalities sodium phosphate enemas, such as Practo-Clyss, should be used with caution or not at all in cats and small dogs.
Source: Tomsa K, Steffen F, Glaus T (2001): Life threatening metabolic disorders after application of a sodium phosphate containing enema in the dog and cat. In: Schweiz Arch Tierheilkd 2001 May;143(5):257-61
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