Twelve dogs naturally infested with S. Scabiei were included in the trial. Diagnosis was based on clinical signs, skin scrapings and/or serology.
All the dogs were treated with a 0.25% fipronil spray, once weekly, for four consecutive weeks, using a total of 12 to 39 mL/kg of spray.
Pruritus and skin lesions disappeared, respectively, seven to 66 days and 14-71 days after the beginning of the treatment.
No relapses occurred during the three to four-month follow-up period.
Three dogs were kept under observation for a further eight to 12-month period with no relapses witnessed.
Of the nine dogs that had been seropositive at the beginning of the study, only two out of six were found to be seronegative when retested three to four months after the end of the treatment.
Source: AF Koutinas, MN Saridomichelakis, N Soubasis, S Bornstein, CK Koutinas (2001): Treatment of canine sarcoptic mange with fipronil spray: A field trial. In: Australian Veterinary Practitioner, 2001, Vol 31, Iss 3, pp 115+
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