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Transformation of a thymic branchial cyst to a carcinoma
Acute dyspnea was the reason for presentating this patient, a 9-year-old, female neutered Dalmatian. Thoracocentesis on presentation yielded 1300 ml sanguineous fluid, while thoracic radiology and ultrasonography showed a mixed-echoic cavitary cranial mediastinal mass, sternal lymph node enlargement and pleural effusion. Not a common finding in a dog of this age!

Surgical exploration of the thorax revealed a multi-lobulated red/brown cranial mediastinal mass and multiple similarly coloured ovoid nodules within several lung lobes.

Histopathology revealed thymic branchial cysts with neoplastic transformation and examination of the lung was consistent with metastasis.

Despite initially recovering well, acute sepsis and pyothorax resulted in cardiac arrest 8 days postoperatively.

This is the first veterinary report of neoplastic transformation of a thymic branchial cyst with pulmonary metastasis.

Source: Levien, A. S., Summers, B. A., Szladovits, B., Benigni, L. and Baines, S. J. (2010), Transformation of a thymic branchial cyst to a carcinoma with pulmonary metastasis in a dog. Journal of Small Animal Practice, 51: 604–608. doi: 10.1111/j.1748-5827.2010.01006.x




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SMALL ANIMAL PRACTICE

Reference intervals for blood parameters in Shetland Sheepdogsmembers
Several breeds have physiological peculiarities that induce variations in reference intervals (RIs) compared with the general canine population. Shetland sheepdogs (SSs) are reported to be more predisposed to different diseases (eg, hyperlipidemia, gallbladder mucocele, and hypothyroidism). Consequently, a breedâ€specific approach is more often required. Thus, the aim of this study was to determine whether the RIs of the general canine population could be applied to that of SSs, and to generate breedâ€specific RIs, where appropriate.

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