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Histopathology in primary glaucomas of Norwegian Elkhounds
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Primary glaucomas in Norwegian Elkhounds are well-known. In this study, the histopatological changes of 31 eyes are described. This breed tends to develop a pectinate ligament dysplasia and/or trabecular meshwork dysplasia as well as a cystic degeneration of the iridociliary epithelial and/or peripheral retina.
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A retrospective histopathologic study of primary glaucoma in the Norwegian Elkhound was undertaken with the study of 9 clinically normal eyes and 22 glaucomatous eyes. All glaucomatous eyes showed goniodysgenesis as manifested by pectinate ligament dysplasia and/or trabecular meshwork dysplasia. Cystic degeneration of the iridociliary epithelial and/or peripheral retina was present in a high percentage of both normotensive and glaucomatous eyes. Utilizing the scheme proposed by Smith et al. (Veterinary and Comparative Ophthalmology 1993; 3: 16-28) the morphology of this disease in the Norwegian Elkhound would be classified as an open-angle, closed-cleft glaucoma, with histopathologic alterations of the outflow pathway similar to that described in other breeds with primary glaucoma.
Source: Yoshie Oshima, Ellen Bjerkas, Robert L. Peiffer Jr (2004): Ocular histopathologic observations in Norwegian Elkhounds with primary open-angle, closed-cleft glaucoma. In: Veterinary OphthalmologyVolume 7 Issue 3 Page 185 - May 2004
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