| |
Repeated administration of propofol in dogs and cats
 |
Propofol has become a very popular drug in small animal medicine and is considered to be a safe and well-tolerated option. But what happens if the drug is administered on consecutive days - is there an accumulation and thus a higher risk? This study on 10 dogs and 10 cats showed no apparent cumulative side effects.
|
|
|
| |
The animals received a bolus of propofol i.v. at the dose of 6 mg/kg (dogs) and 10 mg/kg (cats) for three consecutive days.
The occurence of apnea, heart and respiratory rates, blood pressure, time to movement and biochemical profiles were recorded.
3 cats showed apnea, 6 cats showed a non-significant increase in the number of Heinz bodies.
Based on these results, the authors see no apparent cumulative adverse effects from a bolus of bisulfite-containing propofol, administered on three consecutive days.
Source: Matthews NS et al. (2004): Repetitive Propofol Administration in Dogs and Cats. In: JAAHA 40:4 pp 255-260
Tell a friend
|
Print version
|
Send this article
|
| |
25th FECAVA EuroCongress 4-9 September 2019, St. Petersburg / RussiaESVN-ECVN Symposium 2018ESAVSVetAgendaLab in Practice - Clinical PathologyEuropean Master of Small Animal Veterinary MedicineSEVC 2014ESAVS - Neuropathology & MRICongressMed 2014ACVIM 2014VetContact
|
